特布他林联合阿奇霉素治疗小儿支原体肺炎的疗效临床研究

Clinical Study of Terbutaline Combined with Azithromycin in the Treatment of Mycoplasma Pneumonia in Children

目的:探讨特布他林联合阿奇霉素治疗小儿支原体肺炎的临床疗效。方法:选取2016年3月至2017年7月期间我院收治的60例小儿支原体肺炎患儿作为研究对象,采用随机数表法将其分为对照组(30例)和观察组(30例)。对照组给予阿奇霉素治疗,观察组给予特布他林联合阿奇霉素治疗,比较两组患儿临床治疗效果、炎症因子及症状消失时间。结果:观察组总有效率高于对照组,差异有统计学意义(P<0.05);治疗1个月后,观察组IL-6、IL-8、TNF-α水平均低于对照组,差异有统计学意义(P<0.05);观察组患儿发热、咳嗽、啰音、喘憋症状消失时间均短于对照组,差异有统计学意义(P<0.05)。结论:给予小儿支原体肺炎患儿特布他林联合阿奇霉素治疗效果显著,可有效降低患儿炎症因子水平,促进症状消失,使患儿早日康复。

Objective:To investigate the clinical effect of terbutaline combined with azithromycin in the treatment of mycoplasma pneumonia in children.Methods:From March 2016 to July 2017,60 children with mycoplasma pneumonia were divided into two groups:control group(n=30)and observation group(n=30).The control group was treated with azithromycin and the observation group with terbutaline combined with azithromycin.Results:The total effective rate in the observation group was higher than that in the control group(P﹤0.05).After 1 month,the average water of IL-6,IL-8 and TNF-alpha in the observation group was lower than the control group(P﹤0.05).The disappearance time of fever,cough,rale and asthmatic symptoms in the observation group was shorter than that of the control group(P﹤0.05).Conclusion:The effect of ubutaline combined with azithromycin treatment in children with mycoplasma pneumonia in children was significant.It can effectively reduce the level of inflammatory factors,promote the disappearance of symptoms,and make the children recover soon.