肝血瘀阻证数据挖掘分析研究

Data Mining and Analysis of Blood Stasis of Liver

目的:探明肝血瘀阻证的病位、病性特征,客观揭示肝血瘀阻证的本质,以指导临床辨证,并为病证的规范化及智能化服务。方法:搜集古今文献及临床病案资料179例肝血瘀阻证患者,建立数据库,利用因子分析、关联规则法对资料进行分析,结合专家意见征询研究分析肝血瘀阻证的病位、病性特征。结果:肝血瘀阻证病位特征为胁肋刺痛,胁下痞块,肝掌,蜘蛛痣,腹大坚满,脉弦;病性特征为腹部青筋暴露,面色晦暗或青黑无华,赤丝红缕,痛经,月经量少,闭经,舌质紫黯,有瘀点或瘀斑,脉涩。结论:因子分析、关联规则及专家意见征询等数据挖掘方法可以应用于五脏系统病证规范化研究,可以为病证智能化奠定基础。

Objective:To investigate the disease location and nature of blood stasis of liver and reveal the pathological nature of it objectively in order to guide clinical syndrome differentiation and establish the standardization and intellectualization of the syndrome.Methods:A total of 179 patients with blood stasis of liver were identified by using clinical epidemiological method.We established the database and analyzed the data with factor analysis and association rules to study the disease location and nature of blood stasis of liver combining the experts'opinions.Results:Clinical manifestations such as stabbing pain in ribs,the lump under the ribs,liver palm,spider nevi,hard and unmovable abdomen and taut pulse were the location characteristics of blood stasis of liver.Clinical manifestations such as visible abdominal veins,blackish complexion,silk-like red stripes on the skin,dysmenorrhea,oligomenorrhea,amenorrhea,cyanotic tongue or with cyanotic petechiae and points and astringent pulse were the disease nature characteristics of blood stasis of liver.Conclusion:Different data mining algorithms such as factor analysis,association rules and the experts'opinions should be applied to develop the normalization of five Zang-organs systems.It can lay the foundation for the intellectualization of the syndrome.