316例IVF-ET卵巢低反应患者中医证型分布规律初析

TCM Syndromes of 316 Cases of IVF-ET Poor Ovarian Response Patients

目的:探讨卵巢低反应患者的临床主要证型及主要症状的分布规律。方法:采用临床流行病学研究调查方法,对316例符合纳入标准的卵巢低反应患者进行问卷调查,建立数据库,采用SPSS21.0对数据进行统计分析,寻找卵巢低反应患者主要证型及症状的分布规律,分析卵巢低反应患者常见中医证型与年龄、盆腔手术等的分布情况。结果:其主要中医症状为:性急易怒、腰膝酸软、经血夹块、健忘、神疲力乏、畏寒肢冷、脱发、胸胁胀痛不舒、经前乳房胀痛等;最多的中医证型是肾虚肝郁血瘀证型(占32.7%);单证型中以肾虚证最多(占94.3%);随年龄增加,脾肾两虚肝郁血瘀证出现的几率增大;肾虚肝郁血瘀证及脾肾两虚肝郁血瘀证在有盆腔手术患者中出现的几率均大于无盆腔手术者。结论:IVF-ET卵巢低反应患者的中医常见证型为:肾虚肝郁血瘀证、脾肾两虚肝郁血瘀证、肾虚肝郁证;初步显示随年龄增加,脾肾两肝虚郁血瘀证出现的机率增大;肾虚肝郁血瘀证及脾肾两虚肝郁血瘀证在有盆腔手术患者中出现的几率均大于无盆腔手术者。

Objective:To explore the distribution of the main clinical syndromes and the major symptoms.Methods:By using the method of clinical epidemiological study survey,a total of 316 patients with poor ovarian response were enrolled in this study.And when the building of the database about the 316 patients was finished,this thesis tried to make statistical analysis of the data using SPSS 21.0,and thus investigating the distribution of the main syndromes and symptoms in patients with low ovarian response,and analyzing the distribution of common TCM syndromes and age and pelvic surgery of patients with low ovarian response.Results:The common symptoms of TCM were irritability,backache,menstrual blood clots,amnesia,lack of fatigue,aphrodisiac cold,hair loss,chest pain discomfort,premenstrual breast tenderness,ect.The most TCM syndrome is kidney deficiency and liver depression blood stasis syndrome(32.7%);kidney deficiency amounted the most(94.3%)of the separate syndromes;with the increase of age,the chance of liver depression and spleen deficiency of blood stasis appearred to increase,and the chance of kidney deficiency and blood stasis syndrome and spleen and kidney deficiency liver depression blood stasis in patients with pelvic surgery were more likely to be higher than patients without pelvic surgery.Conclusion:TCM common syndromes of the patients with IVF-ET poor ovarian response are kidney deficiency,liver depression and blood stasis syndrome,spleen and kidney deficiency,liver depression adn blood stasis syndrome and kidney deficiency and liver depression syndrome;with the increase of age,the chance of liver depression and spleen deficiency of blood stasis appears to increase;and kidney deficiency and blood stasis syndrome and spleen and kidney deficiency,liver depression and blood stasis in patients with pelvic surgery were more likely to occur than patients without pelvic surgery.