不同肠内营养供给方式对重度颅脑外伤患者炎症因子及胃肠功能的影响

Effects of Enteral Nutrition with Probiotics on Inflammatory Factors and Gastrointestinal Function in Patients with Severe Traumatic Brain Injury

目的探究不同肠内营养供给方式对重度颅脑外伤患者炎症因子及胃肠功能的影响。方法选取2016年1月～2017年1月我院收治的采用持续泵入输注法进行肠内营养支持的重度颅脑外伤患者71例作为对照组。选取2017年2月～2018年2月我院收治采用间歇输注法进行肠内营养支持的重度颅脑外伤患者71例作为观察组。比较两组护理前后血清炎症因子、胃肠功能变化及并发症发生率。结果观察组护理2周后IL-6、TNF-α水平均低于对照组,差异有统计学意义(P<0.05);观察组护理2周后D-乳酸、PCT水平均低于对照组,差异有统计学意义(P<0.05);观察组并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论以间歇泵入的方法进行肠内营养支持可有效抑制机体炎症反应,保护胃肠功能。

Objective To explore the effect of different enteral nutrition modes on inflammatory factors and gastrointestinal function in patients with severe craniocerebral trauma.Methods From January 2016to January 2017,71patients with severe craniocerebral trauma supported by enteral nutrition were selected as control group,and 71patients with severe craniocerebral trauma supported by enteral nutrition supported by intermittent infusion in our hospital from February 2017to February 2018were selected as the observation group.The serum inflammatory factors,gastrointestinal function and incidence of complications were compared between the two groups before and after treatment.Results After 2weeks of nursing in the observation group,the average IL-6and TNF-alpha water were lower than the control group(P<0.05),and the level of D-lactic acid and PCT in the observation group was lower than that of the control group after 2weeks of Nursing (P<0.05),and the incidence of complications in the observation group was lower than that of the control group(P<0.05).Conclusion Enteral nutrition support by intermittent pump can effectively inhibit the inflammatory reaction and protect gastrointestinal function,which is worthy of clinical promotion.