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吸入用布地奈德混悬液对哮喘急性发作患儿肺功能的影响

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摘要 目的:考查吸入用布地奈德混悬液对哮喘急性发作患儿肺功能的影响。方法:选取本院住院治疗的哮喘急性发作患儿70例,随机分为对照组和治疗组各35例。两组患儿均予以吸氧、平喘、止咳、支气管解痉和抗感染以及纠正电解质紊乱等常规治疗,同时对照组睡前口服孟鲁司特钠咀嚼片,2~5岁患儿4 mg/d,大于5岁患儿5 mg/d。治疗组在对照组基础上采用吸入用布地奈德混悬液1 mg/次,2次/d。两组疗程均为7 d。结果:治疗后两组患儿第1秒用力呼吸容积(FEV1)、呼吸气流量峰值(PEF)、用力肺活量(FVC)较治疗前均有改善,差异有统计学意义(P <0. 05或P <0. 01);治疗后观察组FEV1、PEF、FVC指标改善优于对照组,差异有统计学意义(P <0. 05);观察组哮鸣音、呼吸困难、咳嗽和喘息临床症状消失时间较对照组短,差异有统计学意义(P <0. 05)。结论:吸入用布地奈德混悬液对哮喘急性发作患儿的肺功能具有明显的改善作用,且可明显缩短各临床症状消失时间,可用于哮喘急性发作患儿的治疗。
作者 徐青青
出处 《天津药学》 2018年第6期20-21,共2页 Tianjin Pharmacy
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