单唾液酸四己糖神经节苷脂钠盐注射液联合亚低温对ICU中老年重症脑卒中患者NIHSS评分及血液流变学的影响

Effects of monosialotetrahexosylganglioside sodium salt injection combined with mild hypothermia on NIHSS score and hemorheology in elderly patients with severe stroke in ICU

目的:分析单唾液酸四己糖神经节苷脂钠盐(GM1)注射液联合亚低温对ICU中老年重症脑卒中患者NIHSS评分及血液流变学的影响。方法:将ICU中老年重症脑卒中患者98例,随机平分两组,每组各49例。对照组给予GM1注射液治疗,观察组给予GM1注射液联合亚低温治疗。结果:治疗后两组NIHSS评分均较治疗前降低,且观察组治疗后NIHSS改善程度大于对照组,差异有统计学意义(P<0.05);治疗后观察组AI、BVH、BVM、BVL、PV低于对照组,差异有统计学意义(P<0.05)。结论:GM1注射液联合亚低温可降低ICU中老年重症脑卒中患者NIHSS评分,促进机体功能恢复,改善血液流变学,疗效显著。

Objective:To analyze the effects of monosialotetrahexosyl ganglioside sodium salt(GM1)injection combined with mild hypothermia on NIHSS score and hemorheology in elderly patients with severe stroke in ICU.Methods:98 patients with severe stroke in ICU were selected,they were randomly divided into the two groups equally,the control group was treated with GM1 injection,while the observation group was given GM1 injection combined with mild hypothermia treatment.Results:After treatment, the NIHSS scores of both groups were lower than those before treatment,and the improvement of NIHSS in the observation group was greater than that in the control group(P<0.05).After treatment,the AI,BVH,BVM,BVL and PV in the observation group were lower than those in the control group(P<0.05).Conclusion:GM1 injection combined with mild hypothermia can reduce the NIHSS score of ICU middle-aged and elderly patients with severe stroke,promote the recovery of body function, improve hemorheology, and have a significant effect.