晚期胃癌患者接受序贯甘露聚糖肽联合DCF方案治疗的疗效观察

Observation on the efficacy of sequential mannan peptide combined with DCF regimen in the treatment of patients with advanced gastric cancer

目的:观察晚期胃癌患者接受序贯甘露聚糖肽联合DCF方案治疗的疗效。方法:收治晚期胃癌患者60例,随机平分两组。一组序贯甘露聚糖肽联合DCF方案治疗(序贯治疗组),一组单独DCF方案治疗(单独治疗组),对两组患者的临床疗效、不良反应发生情况进行统计分析。结果:序贯治疗组患者的总缓解率为76.7%,显著高于单独治疗组43.3%(P<0.05);不良反应发生率显著低于单独治疗组(P<0.05)。结论:晚期胃癌患者接受序贯甘露聚糖肽联合DCF方案治疗的疗效较单独DCF方案治疗显著。

Objective:To observe the curative effect of sequential mannan peptide combined with DCF regimen in the treatment of patients with advanced gastric cancer.Methods:60 patients with advanced gastric cancer were selected,they were randomly divided into the two groups equally,a group of sequential mannan peptide combined with DCF regimen(the sequential treatment group),a group of DCF treatment group(the single treatment group),the clinical efficacy and adverse reactions of the two groups were statistically analyzed.Results:The total response rate of the sequential treatment group was 76.7%,which was significantly higher than that of 43.3% in the single treatment group(P<0.05),the incidence of adverse reactions was 3.3%,significantly lower than 33.3% in the single treatment group(P<0.05).Conclusion:Sequential mannan peptide combined with DCF regimen is more effective than DCF regimen alone in the treatment of advanced gastric cancer.