特布他林结合糖皮质激素治疗慢阻肺急性加重期的效果研究

Effect of terbutaline combined with glucocorticoid on acute exacerbation of chronic obstructive pulmonary disease

目的:分析特布他林结合糖皮质激素治疗慢阻肺急性加重期的效果。方法:收治慢阻肺急性加重期患者84例,随机平分两组。均给予常规治疗,对照组加用特布他林治疗,联合组加用特布他林和糖皮质激素治疗,对两组患者的治疗效果、肺功能改善情况、住院时间、不良反应发生情况进行比较。结果:联合组患者治疗总有效率(95.2%)相比于对照组(78.6%)更高,FVC、FEV_1、FEV_1/FVC相比于对照组更高,住院时间相比于对照组更短,组间比较,P<0.05。结论:特布他林联合糖皮质激素治疗慢阻肺急性加重期具有较好的临床疗效,可有效改善其肺功能,加快病情的康复,且药物不良反应较少。

Objective:To analyze the effect of terbutaline combined with glucocorticoid in the treatment of acute exacerbation of chronic obstructive pulmonary disease.Methods:84 patients with acute exacerbation of chronic obstructive pulmonary disease(COPD)were selected,they were randomly divided into the two groups on average,all patients were given routine treatment, the control group was given terbutaline,and the combined group was given terbutaline and glucocorticoid,the therapeutic effect, improvement of pulmonary function,hospitalization time and adverse reactions were compared between the two groups.Results:The total effective rate(95.2%)of the combined group was higher than that of the control group(78.6%).FVC,FEV1,FEV1/FVC were higher than that of the control group,and the hospitalization time was shorter than that of the control group,the comparison between groups(P<0.05).Conclusion:Terbutaline combined with glucocorticoid in the treatment of acute exacerbation of COPD has better clinical efficacy,can effectively improve the lung function,accelerate the recovery of the disease,and with less adverse drug reactions.