中心乳腺叶状肿瘤的病理与临床分析

Pathological and clinical analysis of central breast phyllodes tumor

目的:探讨乳腺叶状肿瘤的临床病理特征,为乳腺叶状肿瘤的诊治提供依据。方法:回顾性分析乳腺叶状肿瘤患者79例的临床病理资料。结果:良性组病程长于交界性组与恶性组,发病年龄低于交界性组与恶性组,肿瘤最大直径与血流阻力指数均小于交界性组与恶性组,差异有统计学意义(P<0.05)。3组肿瘤生长方式、核异型性、肿瘤是否坏死以及间质是否过度生长比较,差异有统计学意义(P<0.05)。结论:乳腺叶状肿瘤以良性病变较多见,掌握乳腺叶状肿瘤的临床病理特征有助于提高乳腺叶状肿瘤术前诊断正确,改善患者预后。

Objective:To investigate the clinicopathological features of breast phyllodes tumor,and to provide the evidence for the diagnosis and treatment of breast phyllodes tumor.Methods:The clinicopathological data of 79 cases of patients with breast phyllodes tumor were analyzed retrospectively.Results:The course of disease in benign group was longer than that in borderline group and malignant group,the age of onset was lower than that in borderline group and malignant group,and the maximum diameter of tumor and the index of blood flow resistance were lower than that in borderline group and malignant group,and the difference was statistically significant (P<0.05).There were significant differences in tumor growth pattern,nuclear atypia,tumor necrosis and interstitial overgrowth among the three groups,and the difference was statistically significant (P<0.05).Conclusion: Benign lesions were more common in breast phyllodes tumor,mastering the clinicopathological features of breast phyllodes tumor was helpful to improve the preoperative diagnosis and prognosis of breast phyllodes tumor.