阴道放置卡孕栓与米索前列醇对宫腔镜子宫黏膜下肌瘤电切术扩张宫颈效果

Effects of vaginal placement of carboprost or misoprostol for cervical dilatation of patients underwent transcervical resection of submucosal myoma by hysteroscopic

目的:分析阴道放置卡孕栓与米索前列醇宫颈预处理对宫腔镜子宫黏膜下肌瘤电切术(TCRM)者宫颈扩张和手术影响。方法:对照性观察本院2015年6月—2017年6月Ⅰ型子宫黏膜下肌瘤(SMU)患者128例,根据术前宫颈预处理方法的不同,分为卡孕栓组和米索前列醇组各64例,于术前分别给予阴道放置卡孕栓或米索前列醇行宫颈预处理。结果:宫颈扩张效果、总有效率卡孕栓组优于米索前列醇组,手术时间、术中出血量卡孕栓组低于米索前列醇组(均P<0.05);两组的药物不良反应发生无差异(P>0.05)。结论:阴道放置卡孕栓宫颈预处理有利于宫腔镜TCRM手术宫颈扩张,减少术中出血量,缩短手术时间,且操作简单快捷、安全有效。

Objective: To analyze the effect of vaginal placement of carboprost or misoprostol for cervical dilatation of patients underwent transcervical resection of submucosal myoma(TCRM) by hysteroscopic. Methods: A comparative study included 128 patients with subumcosal myoma of uterus (SMU) of type I who had admitted to Chongqing women and children health care hospital from June 2015 to June 2017. According to the different methods of preoperative cervical preconditioning, 128 patients were randomly divided into two groups (64 cases in each group). Before operation, the patients in carboprost group were given vaginal placement of carboprost, and the patients in misoprostol group were given vaginal placement of misoprostol. The degree of cervical dilatation and operation situation of patients were compared between the two groups. Results: The effect rate of cervical dilatation and total effective rate of patients in carboprost group were significant better than those of patients in misoprostol group (P<0.05), the operation time of patients in carboprost group was significant shorter than that of patients in misoprostol group (P<0.05), and the amount of bleeding of patients in carboprost group was significant lower than that of patients in misoprostol group (P<0.05), but there was no significant different in the rate of drug adverse reaction between the two groups (P>0.05). Conclusion: Vaginal placement of carboprost is beneficial to patients with SMU before hysteroscopic TCRM, which can reduce the amount of bleeding and shorten the operation time. And vaginal placement of carboprost is easy, safety and effective.