妊娠期母体铁营养状态及铁补充剂应用对围生结局影响的研究进展

Advances in the Effects of Maternal Iron Status and Iron Supplementation during Pregnancy on Perinatal Outcome

铁缺乏是全球最常见的营养不良性问题,妊娠期机体对铁的需求量大幅增加,更容易发生缺铁性贫血,铁补充剂已广泛应用于妊娠期,若使用不当,可能会带来铁营养过剩问题,铁过量也同样会对围生结局产生不良影响。本文回顾了相关文献,对妊娠期铁缺乏、缺铁性贫血及铁过量对围生结局产生影响的研究进展进行总结,指出妊娠期铁缺乏、缺铁性贫血低风险的女性使用铁补充剂的必要性及剂量问题十分重要,但目前国际上对此观点尚不统一,仍需要更多的研究来确定妊娠期补铁的安全性及有效剂量。

Iron deficiency is the most common nutrition problem in the world.The demand for iron is greatly increased in pregnant women,so they are more susceptible to iron deficiency anemia.Iron supplements have been widely used nowadays. But improper use may result in iron overload.And this will also have a negative impact on the perinatal outcome.We reviewed many articles,and summarized the research progress of the impact of maternal iron deficiency,iron deficiency anemia and iron excess during pregnancy on perinatal outcome,and put forward that iron supplementation and the safe dose of iron supplements are very important for women with iron deficiency or low risk of iron deficiency anemia during pregnancy.However,there is no global consensus on the safety of iron supplementation and effective dose of iron supplements for pregnant women,so more relevant studies are needed.