左心室射血分数对心力衰竭患者预后的影响

The Effect of Left Ventricular Ejection Fraction on the Prognosis of Patients With Heart Failure

目的探讨左心室射血分数对心力衰竭患者5年内预后情况的综合分析。方法选取我院于2010年6月—2012年6月收治的368例心衰患者的临床资料进行回顾分析。根据左室射血分数(LVEF)的不同,将其分为射血分数保留型心力衰竭(HFpEF)组(≥50%,110例)、射血分数中间范围型心力衰竭(HFmrEF)组(40%～49%,187例)和射血分数减低型心力衰竭(HFrEF)组(<40%,71例),比较三组患者的一般临床资料和生存曲线。结果三组患者在纽约心脏协会(NYHA)心功能分级、LVEF、LVIDd、TC、TG、LDL-C、HDL-C、收缩压及NT-proBNP相比,差异具有统计学意义(P <0.05);与HFrEF组相比,HFmrEF组和HFpEF组更易合并心房颤动、卒中和糖尿病,差异具有统计学意义(P <0.05);三组患者5年内的存活率相比,差异无统计学意义(P> 0.05)。结论左心室射血分数对心衰患者5年内的预后状况没有显著影响,在临床中应根据情况对该指标进行参考。

Objective To investigate the comprehensive analysis of prognosis in 5 years of left ventricular ejection fraction with heart failure patients. Methods Clinical data of 368 patients with heart failure admitted to our hospital from June 2010 to June 2012 were retrospectively analyzed, accorded left ventricular ejection fraction(LVEF) values were divided into ejection fraction retention heart failure(HFpEF) group(> 50%, 110 cases), ejection fraction intermediate range heart failure(HFmrEF) group(40% ~ 49%, 187 cases) and ejection fraction reduction heart failure(HFrEF) group(< 40%, 71 cases), then to compare the general clinical data and survival curves of the three groups. Results There were significant differences in heart function classification, LVEF, LVIDd, TC, TG, LDL-C, HDL-C, systolic blood pressure and NT-proBNP among the three groups in New York Heart Association(NYHA)(P < 0.05). Compared with HFrEF group, HFmrEF group and HFpEF group were more likely to have atrial fibrillation, stroke and diabetes mellitus(P < 0.05). There was no significant difference in 5-year survival rate among the three groups(P > 0.05). Conclusion Left ventricular ejection fraction(LVEF) has no significant effect on the prognosis of patients with heart failure within 5 years. It should be referred accord to the specific situation.