BISAP评分对急性胰腺炎严重程度及预后评估的临床价值分析

Clinical Value of BISAP Score in Evaluating the Severity and Prognosis of Acute Pancreatitis

目的探讨分析BISAP评分对急性胰腺炎严重程度及预后评估的临床价值。方法将2017年1月—2018年7月该院收治的65例急性胰腺炎患者纳入该次研究,分别利用BISAP评分和Ranson评分对入组对象病情严重程度和预后情况实施评估,对比重症患者与轻症患者、存活病例与死亡病例之间的评分差异,统计BISAP评分和Ranson评分不同分值分组病例的重症急性胰腺炎发生率以及死亡率,评估两组临床疗效。结果入组65例急性胰腺炎患者中,重症患者BISAP评分、Ranson评分分别为(2.09±0.33)分、(3.47±0.29)分,明显高于轻症患者(1.19±0.23)分、(1.68±0.25)分,组间差异有统计学意义(t=-5.370、-7.194,P=0.016、0.011);死亡病例BISAP评分、Ranson评分分别为(3.98±0.35)分、(4.86±0.20)分,明显高于存活病例的(1.44±0.27)分、(2.39±0.16)分,组间差异有统计学意义(t=-6.750、-6.944,P=0.012、0.010); BISAP≥3分者重症急性胰腺炎发病率更高,死亡率更高,与BISAP<3分者相比组间数据差异有统计学意义(χ~2=9.274、13.114,P=0.003、0.001);Ranson≥3分者重症急性胰腺炎发病率更高,与Ranson<3分者相比,差异有统计学意义(χ~2=3.850,P=0.044);Ranson≥3分和BISAP<3分者死亡率差异无统计学意义(χ~2=1.176,P=0.277)。结论 BISAP是临床评估急性胰腺炎患者病情严重程度的常用参考指标,其操作简便易行,还可对急性胰腺炎患者死亡风险做出早期预警,具有积极而重要的参考价值。

Objective To investigate the clinical value of BISAP score in the assessment of severity and prognosis of acute pancreatitis. Methods Sixty-five patients with acute pancreatitis admitted to the hospital from January 2017 to July 2018 were enrolled in the study. The BISAP score and Ranson score were used to evaluate the severity and prognosis of the enrolled patients. Differences in scores between mild patients, surviving cases, and deaths were counted. The incidence of severe acute pancreatitis and mortality were statistically analyzed in different scores of BISAP scores and Ranson scores. The clinical efficacy of the two groups was evaluated. Results Among the 65 patients with acute pancreatitis, the BISAP score and Ranson score were (2.09±0.33)points and (3.47±0.29)points, respectively, which were significantly higher than those of the mild patients (1.19±0.23)points,(1.68±0.25)points points, the difference between groups was significant (t=-5.370,-7.194, P=0.016, 0.011); the BISAP score and Ranson score of death cases were (3.98±0.35)points and (4.86±0.20) points, respectively. Among the surviving cases (1.44±0.27)points and (2.39±0.16)points, the differences between the groups were significant (t=-6.750,-6.944, P=0.012, 0.010); the incidence of severe acute pancreatitis was more in BISAP≥3 points. The mortality was higher, compared with BISAP<3 points, the data difference between groups was statistically significant(χ^2=9.274, 13.114, P=0.003, 0.001); Ranson≥3 points had a higher incidence of severe acute pancreatitis compared with Ranson<3 points, the difference was significant(χ^2=3.850, P=0.044); there was no significant difference in mortality between Ranson≥3 points and BISAP<3 points(χ^2=1.176, P=0.277). Conclusion BISAP is a commonly used reference index for clinical evaluation of the severity of acute pancreatitis patients. It is easy to operate and can provide early warning for the risk of death in patients with acute pancreatitis. It has positive and important reference value.