缺血性脑血管病与颈动脉粥样硬化的相关性分析

Correlation between ischemic cerebrovascular disease and carotid atherosclerosis

目的探讨缺血性脑血管病与颈动脉粥样硬化的相关性。方法回顾分析洛阳市第一人民医院神经内科2012-01—2017-01收治660例缺血性脑血管病患者的临床资料,将其分为脑梗死组和短暂性脑缺血发作组,同时选择560例健康体检者作为对照组,分析3组超声检查情况。结果 3组性别构成、年龄及高血压、高脂血症、糖尿病、冠心病、嗜好烟酒等比较,差异无统计学意义(P>0.05)。CI组斑块检出率为99.6%,TIA组斑块检出率为64.1%,对照组斑块检出率为43.2%,且3组溃疡斑、软斑、硬斑、扁平斑、不稳定斑块和稳定性斑块等检出率比较,差异有统计学意义(P<0.05)。结论缺血性脑血管病的发生与颈动脉粥样硬化有直接联系,加强颈动脉粥样硬化的控制和预防对于缺血性脑血管病发病率的降低具有积极意义。

Objective To investigate the relationship between ischemic cerebrovascular disease and carotid atherosclerosis.Methods This study retrospectively analyzed the clinical data of 660 patients with ischemic cerebrovascular disease admitted to our Department of Neurology from January 2012 to January 2017.They were divided into cerebral infarction group and transient ischemic attack group,and 560 cases were selected at the same time.As a control group,healthy subjects were observed and analyzed in three groups of ultrasound examinations.Results The gender composition,mean age,and the proportion of hypertension,hyperlipidemia,diabetes,coronary heart disease,and hobby alcohol and tobacco in the three groups were not significantly different(P>0.05).The detection rate of plaque in the CI group was 99.6%,the detection rate of plaque in the TIA group was 64.1%,and the detection rate in the control group was 43.2%.The lesions in the three groups were ulcerated,soft,hard,and flat.The detection rates of unstable plaques and stable plaques were statistically significant(P<0.05).Conclusion There is a direct relationship between ischemic cerebrovascular disease and carotid atherosclerosis.Strengthening the control and prevention of carotid atherosclerosis has positive significance for the reduction of the incidence of ischemic cerebrovascular disease.