不同麻醉剂电休克治疗对难治性抑郁症患者心功能的临床观察

Clinical observation of electroconvulsive therapy with different anesthetics in patients with refractory depression

目的:探讨不同麻醉剂电休克治疗方法对难治性抑郁症患者心功能的临床研究。方法:随机选取收治的144例难治性抑郁症患者,其中对照组72例电休克治疗中麻醉剂为丙泊酚;观察组72例难治性抑郁症患者在电休克治疗中采用的麻醉剂为依托咪酯,对比两组患者治疗后的心电图异常以及整个治疗期间的心率情况。结果:两组患者在治疗期间的心电图异常率方面比较,差异无统计学意义(P> 0. 05);两组患者在治疗中较治疗前与治疗后心率明显升高,差异具有统计学意义(P <0. 05),两组患者在不同时间段的心率方面比较,差异无统计学意义(P> 0. 05)。结论:电休克治疗会造成难治性抑郁症患者在治疗期间出现心电图异常,但是在治疗后可快速恢复,不同麻醉剂电休克治疗对难治性抑郁症患者心功能影响差异性较小。

Objective To investigate the clinical effects of different anesthetic agents on electroconvulsive therapy in patients with refractory depression.Method 144 patients with refractory depression were randomly selected,of which 72 cases in the control group were propofol in the treatment of electroconvulsive therapy;in the observation group,the anesthetic agent used in the treatment of electroconvulsive treatment was etomil in 72 patients with refractory depression,compared with the two groups of patients after the treatment of electrocardiogram and the whole period of treatment.The heart rate situation.Results There was no significant difference in the abnormal rate of electrocardiogram between the two groups,and there was no statistical significance(P>0.05).The heart rate of the two groups was significantly higher than that before and after treatment.The difference was statistically significant(P<0.05).The difference between the two groups in the heart rate of different time periods was unclear.There was no statistical significance(P>0.05).Conclusion Electroconvulsive therapy can cause abnormal electrocardiogram in patients with refractory depression during the treatment,but it can recover quickly after treatment.Different anesthetic agents have little difference in heart effect on patients with refractory depression.