喜炎平联合超声透入药物治疗对肺炎患儿C反应蛋白及疗效的影响

Effect of Xiyanping combined with ultrasound penetration drug on C-reactive protein and therapeutic effect in children with pneumonia

目的探讨喜炎平联合超声透入药物治疗对肺炎患儿C反应蛋白及疗效的影响。方法将我院2017年1～12月收治的120例肺炎患儿采用双盲抽签法分为观察组和对照组,每组60例。对照组采用常规治疗。观察组在对照组的基础上采用喜炎平联合超声透入疗法。比较两组治疗前后临床症状积分变化、C反应蛋白(CRP)、降钙素原(PCT)、临床症状消失时间,评价治疗效果及治疗安全性。结果观察组治疗后的主要症候积分低于对照组,治疗后的CRP、PCT均低于对照组,差异有统计学意义(P<0.05)。观察组较对照组的退热时间、肺啰音消失时间、咳嗽消失时间显著缩短,差异有统计学意义(P<0.05)。观察组的临床疗效较对照组显著提高,差异有统计学意义(P<0.05)。结论喜炎平联合超声透入药物治疗能够显著减低肺炎患儿CRP、PCT的水平,改善患儿的临床症状,缩短病程,提高疗效。

Objective To investigate the effect of Xiyanping combined with ultrasound penetration drug on C-reactive protein and therapeutic effect in patients with pneumonia. Methods 120 children with pneumonia admitted in our hospital from January to December 2017 were divided into observation group and control group by double-blind lottery,with 60 cases in each group. The control group received conventional treatment. The observation group was treated with Xiyanping combined with ultrasound penetration therapy on the basis of the treatment of the control group. Changes in clinical symptom scores, C-reactive protein(CRP), procalcitonin(PCT), disappearance of clinical symptoms, evaluation of treatment effects, and treatment safety between two groups before and after treatment were compared. Results The main symptom scores of the observation group were lower than those of the control group. The CRP and PCT of the observation group after treatment were lower than those of the control group, and the difference was statistically significant(P<0.05). The antipyretic time, the disappearance time of the lung sputum, and the disappearance time of cough were significantly shorter in the observation group than those of the control group, and the difference was statistically significant(P<0.05). The clinical efficacy of the observation group was significantly higher than that of the control group, and the difference was statistically significant(P<0.05). Conclusion Xiyanping combined with ultrasound penetration drug can significantly reduce the levels of CRP and PCT in children with pneumonia, improve the clinical symptoms, shorten the course of disease and improve the curative effect.