人工泪液在干眼症中的应用进展

Progress in the application of artificial tears in dry eye syndrome

干眼病患者人群逐年增加,人工泪液依然是干眼症治疗的主流方法 ,然而目前市场上的人工泪液主要以高分子聚合物为活性成分,鲜有活性蛋白及细胞因子的加入,距离理想人工泪液尚远。本文旨在综述人工泪液的现状及近年来天然泪液中发现的活性分子,为开发理想的人工泪液提供思路。

The population of patients with dry eye disease has increased year by year. Artificial tears are still the mainstream method for the treatment of dry eye syndrome. However, artificial tears on the market mainly use high molecular weight polymers as active ingredients, and few active proteins and cytokines are added, which is far from ideal artificial tears. This article aims to review the current state of artificial tears and the active molecules found in natural tears in recent years, in a bid to provide ideas for the development of ideal artificial tears.