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彩色多普勒超声联合人附睾蛋白4与CA125检测在卵巢癌诊断中的价值

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摘要 目的:探讨彩色多普勒超声检查联合人血清附睾蛋白4与糖类抗原CA125在卵巢癌诊断中的价值。方法:卵巢良恶性患者46例(卵巢癌26例,卵巢良性肿瘤20例)进行彩色多普勒超声检查联合人血清附睾蛋白4与糖类抗原CA125血清学检测。结果:卵巢癌患者Alaczar评分8.21±2.14分,高于卵巢良性肿瘤的3.45±1.43分,差异有统计学意义(t=13.46,P<0.05)。卵巢良恶性肿瘤46例中HE4与CA125联合检测均阳性者21例均为卵巢癌,敏感度为80.77%;HE4与CA125联合检测均阴性者18例中卵巢良性肿瘤17例,仅卵巢癌1例,特异度为85.00%。卵巢癌患者中血清HE4与CA125联合检测阳性率均明显高于卵巢肿瘤患者,两者差异性比较有统计学意义(χ2=13.8,P<0.05)。彩色多普勒超声评分检查与人血清附睾蛋白与糖类抗原CA125联合检测呈正相关(r=0.84,P<0.05)。结论:卵巢癌诊断中彩色多普勒超声检查联合人血清附睾蛋白与糖类抗原CA125有着重要的价值。
出处 《交通医学》 2018年第6期585-586,共2页 Medical Journal of Communications
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