多发性恶性血管球瘤1例临床病理分析

Clinical and pathological analysis of one case of multiple malignant glomus tumor

恶性血管球瘤(malignant glomus tumor,MGT)是一种来源于血管周围血管球体的恶性间质性肿瘤。临床上,血管球瘤多为良性,恶性且多中心发生者十分罕见。该文报道1例多发性恶性血管球瘤。患者为75岁女性,先后于乳腺、回肠、大脑及结肠处发生病变,结合光学显微镜下组织形态学检测和免疫组织化学特点分析,该病变均被诊断为MGT。虽多次发病,但经手术切除治疗后患者生存至今。

Malignant glomus tumor(MGT) is a kind of malignant stromal tumor derived from perivascular glomus. Clinically, glomus tumors are mostly benign, malignant and multiple ones are rarely reported. This study reviewed one case of multiple MGT. The lesions were discovered successively in a 75-year-old woman’s breast, ileum, brain and colon. According to the result of histomorphology and immunohistochemistry, the lesions in the four organs were diagnosed as MGT. Suffered from MGT in successive sites, the patient is still alive to date after all of tumors were resected.