急性脑卒中后睡眠障碍的影响因素

Infl uencing factors of sleep disorders after acute stroke

目的:探讨急性脑卒中后睡眠障碍的影响因素。方法:选取急性脑卒中患者326例作为研究对象,根据其出院后是否发生睡眠障碍分为对照组209例和观察组117例。对照组未发生睡眠障碍,观察组发生了睡眠障碍。比较两组性别、年龄、高血压史、糖尿病史、冠心病史、卒中部位、卒中性质、卒中次数、NHISS评分和睡眠障碍的发生率;分析不同卒中类型患者的睡眠障碍类型及影响因素。结果:急性脑卒中后睡眠障碍发生率为35.9%。缺血性脑卒中患者多表现为失眠,出血性脑卒中患者多表现为过度睡眠;观察组年龄、有高血压史、有糖尿病史、有冠心病史者所占比例、NHISS评分均明显高于对照组,卒中次数明显多于对照组,差异均有统计学意义(P<0.05)。Logistic多因素分析结果显示,年龄、有高血压史、糖尿病史、冠心病史、卒中次数、NHISS评分均是急性脑卒中后睡眠障碍的独立影响因素(P<0.05)。结论:急性脑卒中后睡眠障碍的发生率较高,年龄、高血压史、糖尿病史、冠心病史、卒中次数、NHISS评分均为急性脑卒中后睡眠障碍的独立影响因素。

Objective: To investigate infl uencing factors of sleep disorders after acute stroke. Methods: 326 patients with acute stroke were selected as the subjects. According to occurrence of sleep disorders or not, they were divided into control group(n=209, without sleep disorders) and observation group(n=117, with sleep disorders). The gender, age, history of hypertension, history of diabetes, history of coronary heart disease, stroke site, stroke type, stroke frequency, NHISS score, and incidence of sleep disorders were compared between the two groups. The types and infl uencing factors of sleep disorders in the patients with different stroke types were analyzed. Results: The incidence of sleep disorders after acute stroke was 35.9%. The patients with ischemic stroke often showed insomnia, while those with hemorrhagic stroke showed excessive sleep. The age, the proportion of the patients with the history of hypertension, diabetes and coronary heart disease, and the NHISS score of the observation group were signifi cantly higher than those of the control group; the stroke frequency was signifi cantly higher than that of the control group; and the differences were statistically signifi cant(P<0.05). The Logistic multivariate analysis showed that age, history of hypertension, history of diabetes, history of coronary heart disease, stroke frequency, and NHISS score were the independent infl uecning factors of sleep disorders after acute stroke(P<0.05). Conclusions: The incidence of sleep disorders after acute stroke is higher. Age, history of hypertension, history of diabetes, history of coronary heart disease, stroke frequency, and NHISS score are the independent infl uencing factors of sleep disorders after acute stroke.