年龄和月经状态对成年女性骨盆骨髓ADC值的影响

Impact of age and menstrual status on ADC value of pelvic bone marrow in adult women

目的探讨年龄和月经状态对成年女性骨盆骨髓ADC值的影响。方法回顾性分析124例成年女性骨盆骨髓ADC值,其中未绝经组51例,32例年龄>40岁,19例≤40岁;绝经组73例,27例年龄>60岁,46例≤60岁。比较不同月经状态及不同年龄女性之间骨盆骨髓ADC值的差异。结果未绝经组女性骨盆骨髓ADC值高于绝经组(P<0.001);未绝经组中,≤40岁者ADC值高于>40岁者(P<0.001);绝经组≤60岁ADC值与>60岁比较差异无统计学意义(P>0.05)。女性骨盆骨髓ADC值整体上与年龄呈负相关(rs=-0.581,P<0.001),未绝经女性二者呈负相关(rs=-0.301,P=0.032),而绝经后女性二者无显著相关(P>0.05)。结论成年女性骨盆骨髓ADC值随年龄增长而下降,这种趋势在绝经前女性中尤为显著。

Objective To explore the impact of age and menstrual status on ADC value of pelvic bone marrow in adult women.Methods ADC data of pelvic bone marrow in 124 adult women were retrospectively analyzed,including 51 premenopausal women(premenopausal group,32 aged>40 and 19 aged≤40 years)and 73 postmenopausal women(postmenopausal group,27 aged>60 and 46 aged≤60 years).ADC values of pelvic bone marrow in different age and menstrual status of adult women were compared.Results ADC value of pelvic bone marrow in premenopausal group was higher than that in postmenopausal group(P<0.001).In premenopausal group,ADC values in patients aged≤40 years were higher than those>40 years(P<0.001).In postmenopausal group,no significant difference of ADC value was found between women≤60 years and>60 years(P>0.05).ADC value of women's pelvic bone marrow showed negative correlation with age(r s=-0.581,P<0.001),and similar linear correlation was found in premenopausal group(r s=-0.301,P=0.032),whereas no significant correlation was detected between age and ADC value in postmenopausal women(P>0.05).Conclusion ADC value of pelvic bone marrow in adult women decrease with aging,and the tendency is more pronounced in premenopausal women.