摘要
微小RNA(microRNAs,miRNAs)是长度为19～24 nt的内源性非编码小RNA。miRNA与自然杀伤(naturalkiller,NK)细胞的分化和功能密切相关,并参与传染病,肿瘤和其他病理过程的免疫调节。本文对近年来发现的miRNAs在NK细胞发育、分化和功能调控中的作用进行综述。
MicroRNAs(miRNAs)are endogenous non-coding small RNAs that are 19 to 24 nt in length. miRNAs are closely related to the differentiation and function of natural killer (NK) cells and are involved in the immune regulation of infectious diseases,tumors and other pathological processes. In this review, the role of miRNAs discovered in recent years in the development,differentiation and functional regulation of NK cells will be sammarizes.
作者
黄秋萍
袁欢
王宜林
黄庆生
李琦
HUANG Qiuping;YUAN Huan;WANG Yilin;HUANG Qingsheng;LI Qi(Laboratory of National Defense Key Subject of Space Biological Simulation Technology of Northwestern Polytechnical University,Xi'an,Shaanxi,China,710072;Experimental Center of the College of Life, Northwestern Polytechnical University,Xi'an,Shaanxi,China,710072)
出处
《分子诊断与治疗杂志》
2019年第1期63-67,共5页
Journal of Molecular Diagnostics and Therapy
基金
西北工业大学2018年度研究生创意创新种子基金(ZZ2018043)
