气滞血瘀型骨质疏松性骨折临床数据的客观化分析

Objective Analysis of Clinical Data of Osteoporosis Fracture of Qi Stagnation and Blood Stasis Type

目的:观察气滞血瘀型骨质疏松性骨折(OPF)的患者临床数据,分析中医证型与理化指标的关系,为中医辨证分型及疗效标准确立客观化量化指标。方法:选取气滞血瘀型OPF患者241例为A组,肝肾阴虚型OPF患者107例为B组,均采集患者的临床资料及理化指标,分析两组间的差异性。结果:B组血红蛋白水平低于A组,10年髋部骨折及主要OPF发生概率比较均高于A组,比较差异均有统计学意义(P<0.05),两组其他临床理化指标比较差异均无统计学意义(P>0.05)。结论:与肝肾阴虚型OPF患者相比较,气滞血瘀型OPF患者血红蛋白水平较正常或较高,10年髋部骨折发生概率与10年主要OPF发生概率较低,故在基础治疗的基础上,也要及时、针对的治疗具体病症。

Objective:To analyze the correlation between TCM syndrome types and physical and chemical indexes by observing and collecting clinical data of patients with osteoporotic fracture of Qi stagnation and blood stasis type,and to establish objective quantitative indexes for TCM syndrome types and curative effect standards.Method:A total of 241 patients with OPF of qi stagnation and blood stasis type were selected as A group and 107 patients with OPF of yin deficiency of liver and kidney type were selected as B group.The clinical data and physical and chemical indexes were collected and the differences between two groups were analyzed.Result:The hemoglobin level in B group was lower than that of A group,and the incidence of hip fracture and major OPF in 10 years were higher than those of A group,the differences were statistically significant(P<0.05).The other clinical physical and chemical indexes between two groups were compared,the differences were not statistically significant(P>0.05).Conclusion:Compared with patients with OPF of yin deficiency of liver and kidney type,the hemoglobin level of patients with OPF of qi stagnation and blood stasis typeis higher than normal or higher,the incidence of hip fracture and major OPF in 10 years werelower.On the basis of basic treatment,it is also necessary to treat specific diseases in a timely and targeted manner.