缺血性脑血管动脉病溶栓介入治疗临床疗效探讨

Clinical Efficacy of Thrombolysis Interventional Therapy in Ischemic Cerebrovascular Disease

目的评价缺血性脑血管动脉病溶栓介入治疗的临床疗效,为缺血性脑血管动脉病溶栓介入治疗的开展提供参考。方法选择我院2014年2月—2016年2月就诊治疗的84例缺血性脑血管动脉病患者,以随机数字表法分组(对照组、观察组),对照组42例缺血性脑血管动脉病患者接受常用静脉溶栓药物治疗,观察组42例缺血性脑血管动脉病患者接受动脉溶栓介入治疗,对比两组缺血性脑血管动脉病患者随访2年情况(病情平稳状态、再度中风、神经功能损害等情况)。结果观察组缺血性脑血管动脉病患者病情平稳状态良好(95.24%)明显高于对照组(64.28%),再度中风(4.76%)以及神经功能损害(0%)发生率均低于对照组(21.42%、14.29%),P <0.05。结论动脉溶栓介入治疗提高了缺血性脑血管疾病的临床治疗总有效率,利于患者大脑神经功能的改善,降低神经功能损害以及再度中风情况,需重视术前检查、合理应用药物。

Objective To evaluate the clinical efficacy of thrombolytic interventional therapy for ischemic cerebrovascular artery disease,and to provide reference for the development of thrombolytic interventional therapy for ischemic cerebrovascular artery disease.Methods 84 patients with ischemic cerebrovascular disease were selected from February 2014 to February 2016.The patients were divided into control group and observation group by random number table.42 patients with ischemic cerebrovascular artery disease in the control group were treated with intravenous thrombolytic drugs.In the observation group,42 patients with ischemic cerebrovascular artery disease were treated interventional therapy with intra-arterial thrombolysis.patients in the two groups with ischemic cerebrovascular artery disease were followed up for 2 years(stable condition,recurrent stroke,neurological impairment,etc.Results The patients with ischemic cerebrovascular artery disease in the observation group were in good condition.The total effective rate of the patients(95.24%)was significantly higher than that of the control group(64.28%).The incidence of recurrent stroke(4.76%)and neurological impairment(0%)was lower than that of the control group(21.42%and 14.29%,P<0.05).Conclusion Arterial thrombolytic interventional therapy can improve the total effective rate of clinical treatment of ischemic cerebrovascular diseases,improve the neurological function of patients,reduce neurological impairment and re-stroke.It is necessary to pay attention to preoperative examination and rational use of drugs.