摘要
目的探究老年帕金森病患者血清同型半胱氨酸及血尿酸水平与认知功能障碍的相关性。方法选取老年帕金森病患者50例为实验组,所选时间为2017年1月至2017年12月,同时选取老年健康体检者50例为对照组,其均接受血清Hcy(同型半胱氨酸)、UA(血尿酸)水平以及认知功能的检测,对其检测的结果进行分析。结果实验组PD患者的Hcy水平明显高于对照组健康体检者,其UA水平低于对照组,差异有统计学意义(P<0.05);伴认知功能障碍的PD患者,其Hcy水平明显高于不伴认知功能障碍者,其UA水平低于不伴认知功能障碍者,差异有统计学意义(P<0.05)。结论老年帕金森病患者,其血清同型半胱氨酸以及血尿酸水平与其认知功能障碍之间有着密切的联系。
Objective To explore the correlation between serum homocysteine and uric acid levels and cognitive impairment in elderly patients with Parkinson's disease.Methods 50 elderly patients with Parkinson's disease were selected as the experimental group from January 2017 to December 2017,and 50 healthy elderly people were selected as the control group.They were all tested for the levels of serum Hcy(homocysteine),UA(blood uric acid)and cognitive function,and the results were analyzed.Results The Hcy level of PD patients in the experimental group was significantly higher than that of the healthy persons in the control group,and the UA level was lower than that of the control group(P<0.05).The Hcy level of PD patients with cognitive impairment was significantly higher than that of those without cognitive impairment,and the UA level of PD patients with cognitive impairment was lower than that of those without cognitive impairment(P<0.05).Conclusion Serum homocysteine and uric acid levels are closely related to cognitive impairment in elderly patients with Parkinson's disease.
作者
黄碧霞
郭少勇
Huang Bixia;Guo Shaoyong(Department of Neurology,Affiliated Hospital of Putian University,Putian,Fujian,351100,China;Department of Neurology,Putian First Hospital,Putian,Fujian,351100,China)
出处
《当代医学》
2019年第2期100-102,共3页
Contemporary Medicine
