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PET和PET/MRI在阿尔茨海默病中的应用 被引量:5

The applications of PET and PET/MRI in Alzheimer's disease
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摘要 阿尔茨海默病(AD)是老年痴呆最常见的原因,AD的早期诊断有利于改善病人预后。PET和PET/MRI技术在AD的早期诊断和病情评估方面有重要的临床应用价值。现就^(18)F-FDG PET、淀粉样蛋白PET、Tau PET以及PET/MRI在AD方面的发展现状、优势和局限性,以及发展趋势的预测进行综述。 Alzheimer’s disease(AD)is the most common cause of dementia in elderly people.Early diagnosis of AD can improve the prognosis of patients.PET and PET/MRI provide significant contributions to early diagnosis and assessment of AD.The purpose of this paper was to clarify the development status,advantages and limitations of 18F-FDG PET,amyloid PET,Tau PET,and PET/MRI in AD,as well as their possible future trends.
作者 刘思睿 有慧 冯逢 LIU Sirui;YOU Hui;FENG Feng(Department of Radiology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,China)
出处 《国际医学放射学杂志》 北大核心 2019年第1期62-65,共4页 International Journal of Medical Radiology
基金 国家重点研发计划项目(2016YFC1305901)
关键词 阿尔茨海默病 正电子发射体层成像 18F-FDG 淀粉样蛋白 磁共振成像 Alzheimer’s disease Positron emission tomography 18F-FDG Amyloid Magnetic resonance imaging
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  • 1Wang L Zang Y He Y Liang M Zhang X Tian L Wu T Jiang T Li K.Changes in hippocampal connectivity in the early stages of Alzheimer's disease: evidence from resting state fMRI[J].中国生物学文摘,2006,20(10):1-1. 被引量:84
  • 2王铁柱,王宁,马云川.PET脑皮质分区法在AD诊断中的应用[J].中国临床医学影像杂志,2007,18(1):1-4. 被引量:5
  • 3Jia JP, Liu JH. The progress of pathogenesis and treatment of Alzheimer's disease. Chinese Journal of Contemporary Neurology and Neurosurgery, 2010, 10:43-48.
  • 4Johnson KA, Fox NC, Sperling RA, et al. Brain imaging in Alzheirner disease. Cold Spring Harb Perspect Med, 2012,2:a006213.
  • 5McKhann GM, Knopman DS, Chertkow H, et al. The diagnosis of dementia due to Alzheimer' s disease: recommendations from the National Institute on Aging-Alzheimer' s Association workgroups on diagnostic guidelines for Alzheimer' s disease. Alzheimers Dement, 2011,7:263 269.
  • 6Korf ES, Wahlund LO, Visser PJ, et al. Medial temporal lobe atrophy on MRI predicts dementia in patients with mild cognitive impairment. Neurology, 2004,63 : 94-100.
  • 7ManolioTA, Kronmal RA, Burke GL, et al. Magnetic resonance abnormalities and cardiovascular disease in older adults. The Cardiovascular Health Study. Stroke,1994, 25:318-327.
  • 8JiaJ, Sun B, Guo Z, et al. Positron emission tomography with Pittsburgh compound B in diagnosis of early stage Alzheimer' sdisease. Cell Biochem Biophys ,2011,59 : 57-62.
  • 9Mosconi L, Tsui WH, Herh01z K, et al. Multicenter standardized 18F-FDG PET diagnosis of mild cognitive impairment, Alzheimer's disease, and other dementias. J Nucl Med, 2008 49:390- 398.
  • 10Klunk WE, Engler H, Nordberg A, et al. Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. Ann Neurol,2004, 55:306-319.

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