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NSTE-ACS患者心衰程度与血清糖类抗原的相关性研究 被引量：2

Study on correlation between severity of heart failure and serum carbohydrate antigen in patients with NSTE-ACS
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摘要 目的探讨非ST段抬高急性冠脉综合征(NSTE-ACS)患者心衰程度与血清糖类抗原的相关性。方法以126例NSTE-ACS患者为研究对象,其中合并心衰患者(心衰组)和不伴心衰患者(非心衰组)各63例,另选同期于医院体检的80例体检者作为对照(对照组)。比较3组血清糖类抗原125(CA125)、糖类抗原199(CA199)、糖类抗原153(CA153)、B型钠尿肽(BNP)水平和左心室射血分数(EF)值,以及不同纽约心脏协会(NYHA)心功能分级心衰患者之间血清CA125、BNP水平和EF值,并分析糖类抗原与BNP水平和EF值之间的相关性。结果非心衰组血清CA125和BNP水平高于且EF值低于对照组(P <0.05),心衰组的CA125和BNP水平高于且EF值低于非心衰组、对照组(P <0.05)。NYHAⅢ级组血清CA125和BNP水平高于且EF值低于NYHAⅡ级组(P <0.05),NYHAⅣ级组血清CA125和BNP水平高于且EF值低于NYHAⅡ级组、Ⅲ级组(P <0.05)。血清CA125水平与BNP水平呈正相关(r=0.324,P <0.05),与EF呈负相关(r=-0.419,P <0.05),血清BNP水平与EF呈负相关(r=-0.614,P <0.05)。结论血清CA125可作为诊断NSTE-ACS及并发心衰的标志物,可通过监测NSTE-ACS患者血清CA125水平,评估患者的心衰程度。
作者 李丽 蔡文花 韩剑飞 员雅静 唐新龙 李浩
机构地区 迁西县人民医院心血管内科 唐山市工人医院神经外一科
出处 《西南国防医药》 CAS 2019年第1期60-62,共3页 Medical Journal of National Defending Forces in Southwest China
基金 唐山市科学研究与发展计划课题(13130232b)
关键词 非ST段抬高 急性冠脉综合征 心衰 糖类抗原 相关性
分类号 R541.4 [医药卫生—心血管疾病]
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西南国防医药
2019年 第1期

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