甘精胰岛素与二甲双胍治疗初发2型糖尿病伴肥胖症的效果探究

Effect of Insulin Glargine and Metformin on the Treatment of Type 2 Diabetes Complicated with Obesity

目的探究对初发2型糖尿病伴肥胖症患者实施甘精胰岛素与二甲双胍治疗的效果。方法选取2015年3月至2017年10月本院88例初发2型糖尿病伴肥胖症患者为观察对象,结合治疗方式的不同将其分为实验组(48例,应用甘精胰岛素与二甲双胍治疗)、对照组(40例,应用甘精胰岛素治疗)。研究对比实验组和对照组患者的血糖指标、体重指数、血糖达标时间及低血糖发生率。结果实验组患者治疗后空腹血糖、餐后2 h血糖相比对照组明显更低(P<0.05);实验组患者体重指数、血糖达标时间相比对照组明显更少(P<0.05);实验组患者低血糖发生率(12.50%)相比对照组(32.50%)明显更低(P<0.05)。结论对初发2型糖尿病伴肥胖症患者实施甘精胰岛素与二甲双胍治疗的效果更佳。

Objective To investigate the effect of insulin glargine and metformin on patients with newly diagnosed type 2 diabetes associated with obesity.Methods From March 2015 to October 2017,88 patients with type 2 diabetes associated with obesity in our hospital were observed.Combined with the different treatment methods,they were divided into experimental groups(48 cases,using gala Insulin and metformin treatment)and control group(40 cases,treatment with insulin glargine).To compare the blood glucose index,body mass index,blood glucose target time,and incidence of hypoglycemia between the experimental group and the control group.Results Fasting blood glucose and postprandial 2h blood glucose were significantly lower in the experimental group than in the control group(P<0.05).The body mass index and blood glucose reaching time of the experimental group were significantly lower than those in the control group(P<0.05);The incidence of blood glucose(12.50%)was significantly lower than that of the control group(32.50%)(P<0.05).Conclusion Glargine and metformin are more effective in patients with newly diagnosed type 2 diabetes associated with obesity.