心搏骤停后亚低温脑保护的研究进展

Research Progress in Mild Hypothermic Brain Protection after Cardiac Arrest

随着心肺复苏的应用越来越广泛,心搏骤停后患者自主循环恢复的成功率越来越高,但对于入住重症监护病房的患者来说,总体生存率和预后仍较差,其原因主要为不可逆的脑损伤。而亚低温治疗是指通过降低患者核心体温以保护器官,相关研究表明心搏骤停后进行亚低温治疗可以减少脑损伤,促进神经功能恢复及改善总体预后。目前如何在心搏骤停后进行亚低温脑保护的应用及整个治疗过程的管理,是众多研究者全面探索的问题。

With the wide application of cardiopulmonary resuscitation(CPR),the rate of spontaneous circulation restoration in the cardiac arrest patients is becoming higher than before.Whereas,for the patients admitted to the intensive care unit,the overall survival rate is still low and the prognosis is still poor,resulting from the irreversible brain damage.Mild hypothermia therapy can help reduce the core body temperature of the patients so as to protect the organ functions.Recent studies have shown that mild hypothermia therapy can reduce the brain damage,promote neural functional recovery and improve prognosis in patients after cardiac arrest.At present,how to apply hypothermia brain protection and manage the whole treatment process after cardiac arrest is an issue being extensively explored by many researchers.