Q开关532 nm与755 nm激光治疗咖啡斑的疗效对比

Assessment of Therapeutic Efficacy of Q-switched 532 nm and 755 nm Laser in Treatment of Cafe-au-lait

本中心回顾性研究咖啡斑患者84例,随机给予Q开关532 nm和755 nm激光治疗,观察临床效果。结果显示,Q开关532 nm激光治疗36例,痊愈10例(27. 8%),显效10例(27. 8%),有效8例(22. 2%),无效8例(22. 2%); Q开关755 nm激光治疗48例,痊愈14例(29. 2%),显效13例(27. 1%),有效11例(22. 9%),无效10例(20. 8%),84例患者总有效率78. 6%。术后半年随访,色素沉着9例,色素减退3例,复发9例。Q开关激光治疗形状不规则的咖啡斑有效率为79. 5%,治疗形状规则的咖啡斑有效率为52. 5%,两组治疗的有效率差异有统计学意义(P <0. 05),Q开关532 nm激光和Q开关755 nm激光对咖啡斑的治疗效果无显著的统计学差异(P> 0. 05)。以上结果表明,Q开关532 nm激光和Q开关755 nm激光对咖啡斑有明确的治疗效果,且外形不规则的咖啡斑治疗效果好。

Eighty four patients with cafe-au-lait were treated with Q-switched 532 nm or 755 nm laser randomly by our center.The clinical efficacy was assessed.36 patients were treated with Q-switched 532 nm laser,10 patients were completely cured (27.8%),10 patients were significantly improved (27.8%),8 improved (22.2%) and 8 invalid (22.2%);48 patients were treated with Q-switched 755 nm laser,14 patients were cured completely (29.2%),13 patients were significantly improved (27.1%),11 improved (22.9%) and 10 invalid (20.8%).Of the 84 patients,total effective rate is 78.6%.After 6 months of follow-up,9 patients appeared pigmentation,3 patients appeared hypopigmentation and 9 recrudesced.The effective rate of cafe-au-lait with regular shape is 52.5%,and irregular shape is 79.5%,there was a significant difference between two teams (P<0.05).There was no significant difference in efficacy between Q-switched 532 nm and 755 nm laser (P>0.05).The above results showed Q-switched 532 nm and 755 nm laser were effective agents for treatment of cafe-au-lait.,and the efficacy of Q-switched laser on cafe-au-lait with regular shape is better than those with irregular shape.