替吉奥治疗进展期胃癌的临床疗效分析

Clinical Effect Analysis on Advanced Gastric Cancer Treated by S-1

目的探讨替吉奥治疗进展期胃癌的临床效果。方法选取我院收治的进展期胃癌患者140例,随机分为两组,研究组应用替吉奥治疗,对照组应用奥沙利铂治疗。比较两组患者的临床疗效、不良反应发生率、生活质量。结果研究组临床疗效优于对照组,差异有统计学意义(P<0.05);研究组不良反应发生率低于对照组,差异有统计学意义(P<0.05);研究组生活质量高于对照组,差异有统计学意义(P<0.05)。结论替吉奥对进展期胃癌患者的治疗效果较好,值得临床推广使用。

Objective To investigate the clinical effect of S-1 in the treatment of advanced gastric cancer.Methods 140 patients with advanced gastric cancer treated in our hospital were randomly divided into two groups.The study group was treated with S-1,and the control group was treated with oxaliplatin.The clinical efficacy,incidence of adverse reactions and quality of life were compared between the two groups.Results The clinical efficacy was higher in the study group than in the control group(P<0.05).The incidence of adverse reactions in the study group was lower than in the control group(P<0.05).The quality of life in the study group was higher than in the control group(P<0.05).Conclusion S-1 achieved a good therapeutic effect in the treatment of patients with advanced gastric cancer.