期刊文献+

结合靶向药物综合治疗结肠癌肝及肝外转移术后7年1例报告

Combined with Targeted Drugs for the Treatment of Colon Cancer Liver and Extrahepatic Metastases in 7 Years after A Report of 1 Case
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摘要 结肠癌(colon cancer)是最常见癌症之一,大约35%的患者伴肝转移,结肠癌肝转移(CRLM)患者中位生存期仅6~12个月[1]。对有手术切除机会的结肠癌肝或肝外转移的患者,手术切除依然是结肠癌转移患者唯一获得长期生存的手段。有文献报道,对早期结肠癌手术切除术后5年生存率可达50%~80%[2]。然而,对结肠癌肝及肝外转移患者单一手术切除病灶,术后肿瘤复发率极高,严重影响患者生存期。近年来,随着分子生物学和介入放射学科的发展,更多更有效的靶向药物及先进的介入治疗(如RFA、TACE)应用于结肠癌肝及肝外转移患者,使得患者生存率得到一定程度提高[3]。目前,对结肠癌肝及肝外转移术后行靶向药物联合RFA、TACE综合治疗方案的报告不多,我科对1例患者病灶切除术后结合靶向药物等综合治疗长期生存(约7年),疗效满意,现报告如下。
作者 黄富全
出处 《医学信息》 2019年第1期186-188,共3页 Journal of Medical Information
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