香料烟云香巴斯玛1号的化学成分研究

Studies of Chemical Constituents from Oriental Tobacco YNOTBS1

【目的】研究香料烟云香巴斯玛1号下部叶的化学成分。【方法】云香巴斯玛1号下部叶的甲醇提取物经过乙酸乙酯萃取后,再利用硅胶柱色谱及半制备HPLC等进行分离纯化,并通过波谱分析鉴定分离的化学成分。【结果】从该植物中分离得到7个化合物,其结构分别鉴定为:邻苯二甲酸二异丁酯(1)、邻苯二甲酸二丁酯(2)、(+)-sclareolide (3)、14,15-dinor-8-labdene-7,13-dione (4)、α-levantenolide (5)、β-levantenolide (6)、8-hydroxy-14,15-dinor-11-labden-13-one (7)。【结论】以上化合物均为首次从该植物中分离得到。

[Purpose]In order to investigate the chemical constituents from lower leaves of oriental tobacco YNOTBS1.[Method]Compounds were isolated from methanol extraction of lower leaves of oriental tobacco YNOTBS1 by extracting with ethyl acetate and using silica gel column chromatography and preparative HPLC.Their structures were identified by spectral analysis.[Results]Seven compounds were isolated from this plant.Their structures were identified as phthalic acid isodibutyl ester(1),dibutyl phthalate(2),(+)-sclareolide(3),14,15-dinor-8-labdene-7,13-dione(4),α-levantenolide(5),β-levantenolide(6)and 8-hydroxy-14,15-dinor-11-labden-13-one(7).[Conclusion]All compounds were obtained from this plant for the first time.