新鲜冰冻血浆使用合理性及有效性回顾性分析

Retrospective Analysis of Appropriateness and Effectiveness of Fresh Frozen Plasmaused

目的通过对本院2016年4月～2017年3月新鲜冰冻血浆使用情况进行回顾性分析,了解血浆使用合理性及有效性,指导临床合理用血。方法通过医院信息系统收集2016年4月～2017年3月新鲜冰冻血浆使用情况及相关信息,根据评价标准判断血浆使用的合理性及有效性,并对全院新鲜冰冻血浆使用情况进行调查分析。结果新鲜冰冻血浆输注合理率49.2%,输注有效率33.9%。手术科室与非手术科室输注合理率和有效率的差异无统计学意义,合理与不合理输注有效率的差异有统计学意义。新鲜冰冻血浆不合理使用主要是搭配输血、INR<正常1.5倍患者出血以及无出血患者的预防性输注。结论新鲜冰冻血浆不合理输注现象较严重,不合理输注有效率低,医院输血管理委员会应发挥作用,加强全院用血情况的监测与分析,对临床用血进行培训与督导,提高血浆输注的合理性及有效性。

Objective To analyze the usage of fresh frozen plasma(FFP)in our hospital from April 2016 to March 2017,and to realize the appropriateness and effectiveness of FFP transfusion.Method Data werecollected through the hospital information system.The appropriateness and effectiveness of FFP transfusion was analyzed according to the evaluation criteria.Result Audit of FFP used shows appropriate utilization rate of 49.2%and effective rate of 33.9%in our hospital,No significant difference is found between surgical departments and non-surgical departments.There existed significant difference between the effectiveness rate of appropriate transfusion and inappropriate transfusion.The three largest reasons for inappropriate use were collocation of blood transfusion,active bleeding with INR<1.5 normal and the transfusion of FFP in the absence of bleeding.Conclusion Inappropriate usage of FFP is more and the effective rate of inappropriate transfusion is low.The hospital blood transfusion committees should be play an important role in monitoring the use of blood,training and supervising the medical staff,that helpfulimprove the appropriateness and effectiveness of FFP transfusion.