泮托拉唑与奥美拉唑治疗消化性溃疡合并出血的疗效分析

Efficacy Analysis of Pantoprazole and Omeprazole in the Treatment of Peptic Ulcer Complicated with Hemorrhage

目的分析泮托拉唑与奥美拉唑治疗消化性溃疡合并出血的疗效。方法选择该院自2015年1月—2017年12月收治的195例消化性溃疡合并出血患者,将其随机分为2组,对照组98例,观察组97例。对照组给予奥美拉唑加康复新液治疗,观察组给予泮托拉唑针加康复新液治疗,对两组治疗效果进行比较。结果观察组患者临床有效率为97.94%明显高于对照组80.61%,相对比,差异有统计学意义(χ~2=11.398 3,P<0.05);观察组不良反应发生率为5.15%明显低于对照组11.22%,差异有统计学意义(χ~2=8.782 1,P<0.05)。结论消化性溃疡合并出血的患者,泮托拉唑与奥美拉唑均有一定的疗效,但前者疗效更为显著。

Objective To analyze the efficacy of pantoprazole and omeprazole in the treatment of peptic ulcer combined with hemorrhage.Methods A total of 195 patients with peptic ulcer complicated hemorrhage admitted to the hospital from January 2015 to December 2017 were randomly divided into 2 groups,98 in the control group and 97 in the observation group.The control group was treated with omeprazole plus rehabilitation new fluid,and the observation group was given pantoprazole needle plus rehabilitation new fluid treatment.The therapeutic effects of the two groups were compared.Results The clinical effective rate of the observation group was 97.94%,which was significantly higher than that of the control group 80.61%(χ^2=11.398 3,P<0.05).The incidence of adverse reactions in the observation group was 5.15%,which was significantly lower than that in the control group 11.22%(χ^2=8.7821,P<0.05).Conclusion Pantoprazole and omeprazole have certain curative effects in patients with peptic ulcer complicated with hemorrhage,but the former is more effective.