640层容积CT评估肺动脉弹性及其与主动脉弹性的相关性

Pulmonary Artery Elasticity Evaluated by 640-slice Volume CT and Its Correlation with Aortic Elasticity

目的探讨640层容积CT在肺动脉弹性评估中的可行性及其与主动脉弹性的相关性。资料与方法前瞻性收集2015年10月—2016年4月于我院行640层容积冠状动脉CT血管成像检查且符合纳入和排除标准的42例受检者。测量主肺动脉(MPA)、升主动脉(AA)、降主动脉(DA)感兴趣区管腔在收缩期与舒张期的最大及最小横截面积,计算弹性参数动脉扩张度(AD)。比较各血管间的AD值,分析各参数间的相关性。结果随心脏搏动,主肺动脉管径发生周期性变化。MPA、AA、DA的弹性不同,AD值依次为(7.94±3.04)×10^(-3)/mmHg、(4.02±2.16)×10^(-3)/mmHg和(3.23±1.46)×10^(-3)/mmHg。AA与DA、AA与MPA、DA与MPA呈正相关(r=0.689、0.520、0.393,P<0.001、P<0.05)。结论 640层容积CT结合回顾性心电门控技术可以在无需额外增加辐射剂量和对比剂用量的前提下,完成肺动脉弹性的评估,且肺动脉与主动脉弹性具有较好的相关性。

Purpose To explore the feasibility of 640-slice volume CT in the assessment of pulmonary artery elasticity and its correlation with aortic elasticity.Materials and Methods Forty-two subjects who underwent 640-slice volume CT coronary artery CTA examination in our hospital from October 2015 to April 2016 were prospectively admitted in this study according to the inclusion and exclusion criteria.The maximum and minimum cross-sectional area of region of interest(ROI)lumen of the main pulmonary artery(MPA),ascending aorta(AA),and descending aorta(DA)in the systolic and diastolic phases were measured,and the elastic parameter artery distensibility(AD)was calculated.The AD values among the blood vessels were compared,and the correlations among different parameters were analyzed.Results The main pulmonary artery diameter changed periodically along with cardiac impulse.As the elasticity of MPA,AA and DA varied,and the AD values were(7.94±3.04)×10^-3/mmHg,(4.02±2.16)×10^-3/mmHg,and(3.23±1.46)×10^-3/mmHg,respectively.The AA and DA,AA and MPA,DA and MPA showed a positive correlation(r=0.689,0.520 and 0.393,P<0.001 and P<0.05),respectively.Conclusion The 640-slice volume CT combined with retrospective ECG-gating technique can complete the assessment of pulmonary artery elasticity without additional addition of radiation dose and contrast agent dosage,and the pulmonary artery has good correlation with aortic elasticity.