探析他汀类联合心血管药物治疗冠心病的疗效

Efficacy of Statins Combined With Cardiovascular Drugs in the Teatment of Coronary Heart Disease

目的分析他汀类联合心血管药物治疗冠心病的临床疗效及对不良反应发生率的影响。方法将到我院诊治的166例冠心病患者选入本次研究,设立研究组、常规组,入院号为单数的患者归入研究组,双数的患者归入常规组,每组有83例,两组均应用常规心血管药物治疗,研究组在常规治疗的基础上结合瑞舒伐他汀治疗,观察两组患者的治疗效果、不良反应发生情况,对两组治疗前后的三酰甘油(TG)、总胆固醇(TC)、低密度脂蛋白(LDL-C)、高密度脂蛋白(HDL-C)水平进行统计。结果统计分析两组治疗有效率发现,研究组为98.80%,高于常规组的86.75%;对比不良反应发生情况,研究组不良反应率低于常规组(3.61%<12.05%);研究组治疗后的TG、TC、LDL-C、HDL-C各项水平改善更显著,P <0.05。结论他汀类联合心血管药物治疗冠心病的临床疗效优秀,不良反应发生情况较少。

Objective To analyze the clinical efficacy of statins combined with cardiovascular drugs in the treatment of coronary heart disease(CHD)and the incidence of adverse reactions.Methods 166 patients with coronary heart disease were selected to study the scope of the study,the study group and the routine group were set up,the number of patients with a single number was classified into the study group,and the patients of the double number were classified into the routine group,with 83 cases in each group,and the two groups were all treated with conventional cardiovascular medicine.The study group plan was combined with Rui on the basis of conventional treatment.The treatment effect and adverse reaction of two groups were observed and the levels of three acy l glycerol(TG),total cholesterol(TC),low density lipoprotein(LDL-C)and high density lipoprotein(HDL-C)were measured before and after treatment in the two groups.Results Statistical analysis showed that the effective rate of treatment in the study group was 98.80%,higher than 86.75%in the routine group.Compared with the occurrence of adverse reactions,the rate of adverse reactions in the study group was lower than that in the conventional group(3.61%<12.05%).After treatment,the levels of TG,TC,LDL-C and HDL-C in the study group improved significantly(P<0.05).Conclusion Statins combined with cardiovascular drugs are effective in the treatment of coronary heart disease,and the incidence of adverse reactions is less.