基因多态性与胃癌的相关性研究

Relationship between gene polymorphisms and gastric cancer

胃癌是最普遍的人类消化道恶性肿瘤之一,在世界范围内,胃癌的发病率在恶性肿瘤中排第四位,也是导致全球癌症直接死亡的第二大主要原因。胃的癌变是多因素相互作用、循序渐进的发展过程,近几年来,从基因多态性方面研究胃癌易感性已成为热点,为胃癌的早期诊断、基因治疗、改善预后提供了依据。

Gastric cancer is one of the most common human digestive tract malignancies.The incidence of gastric cancer ranks the fourth among malignancies and it is the second leading cause of direct cancer death worldwide.Carcinogenesis of the stomach is a multi-factor interaction and gradual development process.In recent years,the study of gastric cancer susceptibility has become a hot spot for gene polymorphism,providing a basis for early diagnosis of gastric cancer,gene therapy,and improving prognosis.