Solitaire AB支架取栓和静脉溶栓治疗心源性脑栓塞的疗效及安全性对比

Efficacy and Safety of Solitaire AB Stent Thrombectomy and Intravenous Thrombolysis for Cardiogenic Cerebral Embolism

目的比较Solitaire AB支架取栓和静脉溶栓治疗心源性脑栓塞的疗效。方法根据入组标准选择该院2015年6月—2018年6月期间收治的66例心源性脑栓塞患者为研究对象,随机分为两组,每组33例。对照组接受静脉溶栓治疗,观察组接受Solitaire AB支架取栓治疗。统计两组患者血管再通率,采用神经功能缺损评分(NIHSS)评价治疗前后两组患者神经功能改善情况。记录两组患者并发症的发生情况。结果观察组患者血管再通率93.94%显著高于对照组的75.76%(χ2=4.242 9,P<0.05)。治疗前,两组患者NIHSS评分比较差异无统计学意义(P>0.05);治疗后,观察组NIHSS评分(10.25±1.34)分较对照组(14.28±1.72)分有明显改善(t=7.146 2,P<0.05)。观察组患者并发症发生率9.09%显著低于对照组30.30%(χ2=4.693 7,P<0.05)。结论相较于静脉溶栓,Solitaire AB支架取栓的效果更好,且安全性高,值得推广。

Objective To compare the efficacy of Solitaire AB stent thrombectomy and intravenous thrombolysis for cardiogenic cerebral embolism.Methods According to the enrollment criteria,66 patients with cardiogenic cerebral embolism admitted to our hospital from June 2015 to June 2018 were randomly divided into two groups,33 in each group.The control group received intravenous thrombolysis,and the observation group received Solitaire AB stent thrombectomy.The vascular recanalization rate was calculated in the two groups.The neurological deficit score(NIHSS)was used to evaluate the improvement of neurological function in the two groups before and after treatment.The incidence of complications in the two groups was recorded.Results The recanalization rate of the observation group was 93.94%significantly higher than that of the control group 75.76%(χ2=4.242 9,P<0.05).Before treatment,there was no difference in NIHSS score between the two groups(P>0.05).After treatment,the NIHSS score of the observation group was(10.25±1.34)points compared with the control group of(14.28±1.72)points(t=7.146 2,P<0.05).The complication rate of 9.09%in the observation group was significantly lower than that in the control group(30.30%)(χ2=4.693 7,P<0.05).Conclusion Compared with intravenous thrombolysis,Solitaire AB stent is better and safer,and it is worthy of promotion.