手术治疗老年骨质疏松性椎体压缩性骨折的临床效果及安全性

Clinical effect and safety of surgical treatment of osteoporotic vertebralcompression fractures in the elderly

目的探讨老年骨质疏松性椎体压缩性骨折实施经皮椎体后凸成形术(PKP)和经皮椎体成形术(PVP)的临床效果和安全性。方法选取2016年1月至2018年5月医院收治的244例老年骨质疏松椎体压缩性骨折患者作为研究对象,按照手术方式不同将其分为PKP组(126例,PKP治疗)和PVP组(118例,PVP治疗)。比较两组患者的临床治疗效果。结果两组患者治疗总有效率比较,差异无统计学意义(P>0.05);PKP组术后并发症总发生率为4.76%,低于PVP组的12.71%,差异具有统计学意义(P<0.05);PKP组患者术后VAS评分低于PVP组,但PKP组住院费用高于PVP组,差异具有统计学意义(P<0.05)。结论 PKP和PVP治疗老年骨质疏松椎体压缩性骨折的效果相当,但前者造成的并发症少,缓解疼痛更有效,而后者住院费用较低,应根据患者的实际情况选择治疗方法。

Objective To investigate the clinical effect and safety of percutaneous kyphoplasty (PKP) and percutaneous vertebroplasty (PVP) in elderly patients with osteoporotic vertebral compression fractures.Methods A total of 244 elderly patients with osteoporotic vertebral compression fractures admitted in the hospital from January 2016 to May 2018 were selected as the study objects,they were divided into PKP group (n=126,PKP treatment) and PVP group (n=18,PVP treatment) according to the different surgical methods.The clinical treatment effects of the two groups were compared.Results There was no significant difference in the total effective rates of treatment between the two groups (P>0.05).The total incidence of postoperative complications in the PKP group was 4.76%,which was lower than 12.71% in the PVP group,and the difference was statistically significant (P<0.05).The VAS score of the PKP group was lower than that of the PVP group,but the hospitalization cost of the PKP group was higher than that of the PVP group,and the differences were statistically significant (P<0.05).Conclusion PKP and PVP are both effective in the treatment of osteoporotic vertebral compression fractures in the elderly,but the former causes fewer complications and alleviates pain more effectively,while the latter has lower hospitalization costs.Treatment methods should be chosen according to patients' actual conditions.