进展性脑梗死脑侧支循环形成及其对近期神经功能的影响效果分析

Analysis of the Formation of Collateral Circulation in Progressive Cerebral Infarction and Its Effect on Recent Neurological Function

目的观察进展性脑梗死脑侧支循环形成及探讨其对于近期神经功能的影响效果。方法方便选取2015年5月—2018年5月间该院收治200例急性脑梗死患者的头部CTA影像结果作为研究资料,分析其侧支循环形成的情况,并分为进展性脑梗死组(n=57)以及非进展性脑梗死组(n=143)。评价患者被收治入院以及治疗14 d神经功能的缺损程度以及日常活动能力,探讨侧支循环形成对于患者近期神经功能的影响效果。结果在急性脑梗死患者当中,进展性脑梗死占28.5%(57/200)、非进展性脑梗死占71.5%(143/200)。其中脑梗死进展性患者侧支循环的形成几率相比于非进展性患者更低(P<0.05)。治疗后14 d,有侧支循环形成的患者近期神经功能情况明显优于无侧支循环形成患者(χ2=7.649 6、9.949 6,P<0.05);治疗后14 d,有侧支循环形成的患者近期神经功能评分明显优于无侧支循环形成患者(t=3.932、2.595,P<0.05)。结论对于进展性患者的侧支循环形成状况相对于非进展性患者更差;在急性脑梗死患者中无侧支循环形成者近期的神经功能恢复相对差,此类患者病情更容易出现进展。

Objective To observe the formation of collateral circulation in patients with progressive cerebral infarction and to explore its effect on recent neurological function.Methods From May 2015 to May 2018,the results of head CTA imaging in 200 patients with acute cerebral infarction were convenient selected as the research data.The formation of collateral circulation was analyzed and divided into progressive cerebral infarction group (n=57) and non-progressive cerebral infarction (n=143).To evaluate the extent of the patient's admission to the hospital and the 14 d neurological deficit and daily activity,and to explore the effect of collateral circulation on the patient's recent neurological function.Results Among patients with acute cerebral infarction,progressive cerebral infarction accounted for 28.5%(57/200) and non-progressive cerebral infarction accounted for 71.5%(143/200).The incidence of collateral circulation in patients with progressive cerebral infarction was lower than that in non-progressive patients(P<0.05).At 14 days after treatment,the patients with collateral circulation had a significantly better neurological function than those without collateral circulation (χ^2=7.649 6,9.949 6,P<0.05).At 14 days after treatment,patients with collateral circulation were recently neurological function score was significantly better than that of patients without collateral circulation (t=3.932,2.595,P<0.05).Conclusion The formation of collateral circulation in progressive patients is worse than that in non-progressive patients; in patients with acute cerebral infarction,the recovery of neurological function in patients with no collateral circulation is relatively poor,and such patients are more likely to progress.