穴位埋线联合强脉冲光治疗黄褐斑的临床效果

Clinical effect of acupoint embedding combined with intense pulsed light in the treatment of chloasma

目的观察穴位埋线联合强脉冲光治疗黄褐斑的效果。方法选取2016年12月～2017年11月我院收治的120例黄褐斑患者作为研究对象,按照随机数字表法将其分为治疗组(60例)与对照组(60例),治疗组患者予辨证穴位埋线联合强脉冲光治疗,强脉冲光每个月治疗1次,并予治疗前半小时辨证穴位埋线,对照组患者单给予强脉冲光治疗,每个月治疗1次,疗程均为5个月。比较两组患者治疗前后的黄褐斑面积和严重指数(MASI)评分及治疗总有效率;比较两组患者治疗前后的皮肤检测仪(VISIA)图像分析系统评分绝对值及皮肤色斑改善变化率;比较两组患者的不良反应发生情况;比较两组患者的复发率。结果治疗后,两组患者的MASI评分、VISIA图像分析系统评分绝对值低于治疗前,差异有统计学意义(P<0.05)。治疗组患者治疗后的MASI评分、VISIA图像分析系统评分绝对值低于对照组,差异有统计学意义(P<0.05)。治疗组患者的治疗总有效率为82.46%,高于对照组的53.45%,差异有统计学意义(P<0.01)。治疗组患者的皮肤色斑改善变化率高于对照组,差异有统计学意义(P<0.05)。两组患者均未出现严重不良反应。随访12周,治疗组患者的复发率为7.0%,低于对照组的15.5%,差异有统计学意义(P<0.05)。结论黄褐斑应用穴位埋线和强脉冲光联合治疗能提高临床疗效,并且降低复发率。

Objective To observe the clinical effect of acupoint embedding combined with intense pulsed light in the treatment of chloasma.Methods A total of 120 patients with chloasma treated in our hospital from December 2016 to November 2017 were selected as subjects,and they were divided into the treatment group(60 cases)and the control group(60 cases)according to the random number table method.The treatment group was treated with syndrome differentiation acupoint embedding combined with intense pulsed light therapy once a month,and syndrome differentiation acupoint embedding was conducted half an hour before light therapy,while the control group was treated with intense pulsed light alone once a month with a course of 5 months.The chloasma area and severity index(MASI)score before and after treatment and the total effective rate of treatment were compared between the two groups.The absolute value of the VISIA image analysis system score before and after treatment and the improvement rate of skin pigmentation were compared between the two groups.The adverse reactions of the two groups were compared.The recurrence rates of the two groups were compared.Results After treatment,MASI score and VISIA image analysis system absolute score in both groups were lower than those before treatment,the differences were statistically significant(P<0.05).MASI score and VISIA image analysis system absolute score were lower in the treatment group than those in the control group,the differences were statistically significant(P<0.05).The total effective rate of the treatment group was 82.46%,which was higher than 53.45%of the control group,the difference was statistically significant(P<0.01).The improvement rate of skin pigmentation in the treatment group was higher than that in the control group,the difference was statistically significant(P<0.05).No serious adverse reactions occurred in either group.After 12 weeks of follow-up,the recurrence rate of patients in the treatment group was 7.0%,which was lower than 15.5%in the control group,and the difference was statistically significant(P<0.05).Conclusion The combined treatment of chloasma with acupoint embedding and intense pulsed light can improve clinical efficacy and reduce recurrence rate.