摘要
在色谱分析过程中,利用串联、并联或串并联结合的方式将多根色谱柱组合起来,可以实现高通量和高分辨的分离效果。相比于传统单柱色谱技术,多柱技术很好地满足了批量样品分析和复杂生物样品分离分析的需求,因此引起了广泛关注。该文对多柱技术在多维分离、芯片色谱、毛细管电泳、固定相筛选以及串联色谱等领域的应用进行了综述,并对其发展前景进行了展望。
Multi-column chromatographic technologies provide high throughput and high resolu-tion separations through parallel, serial or parallel-serial column combinations. In comparison with classical single-column based chromatography, multi-column chromatography well satis-fied the need for separations of large batch samples and highly complex bio-samples,and there-fore attracted extensive interests. In this review, we discussed the recent developments in multi-column chromatography and its applications in multidimensional separation, chip chroma-tography, capillary electrophoresis, stationary-phase screening, and serial column chromatogra-phy. We also discussed the limitations and future developments in mjiilti-column chromatography.
作者
王晓飞
孙楷越
张博
WANG Xiaofei;SUN Kaiyue;ZHANG Bo(College of Chemistry &Chemical Engineering, Xiamen University, Xiamen 361005, China)
出处
《色谱》
CAS
CSCD
北大核心
2019年第2期123-131,共9页
Chinese Journal of Chromatography
基金
国家自然科学基金(21475110
21535007
J1310024)
中国博士后基金项目(2018M642572)
厦门市科技计划项目(3502Z20173019)
中央高校基本科研业务费(20720160051)~~
关键词
多柱色谱
串/并联色谱柱
高通量
芯片色谱
多维色谱
综述
multi-column chromatography
parallel/serial columns
high-throughput
chip separation
multidimensional chromatography
review
