不同年龄及性别体检人群体内矿物质含量分析

Comparative analysis of human body mineral content among individuals of different age and gender

目的探讨成年人体内各矿物质含量在不同年龄及性别间的差异,为个体化矿物质补充及调节提供理论依据。方法选取自2016年5月至2017年12月在北部战区总医院健康管理中心进行健康体检者914例为研究对象。按年龄将研究对象分为6组:18～29岁组(n=18)、30～39岁组(n=95)、40～49岁组(n=295)、50～59岁组(n=311)、60～69岁组(n=171)及年龄≥70岁组(n=24)。分别对各组受检者体内总矿物质含量,血液中铜、铁、镁、锌、钙、钾、钠、氯浓度及骨密度T值、Z值进行测定,并分析比较其体内各矿物质含量在不同年龄、性别间的差异。结果不同性别间总矿物质含量、Z值、铁、镁、锌、钾、钠、氯的分布比较,差异有统计学意义(P <0. 05);同性别不同年龄组比较发现,总矿物质含量、骨密度T值、骨密度Z值、镁、铁的分布不同,组间比较,差异均有统计学意义(P <0. 05)。体内总矿物质含量在40岁之后随年龄增加而逐渐减少;女性骨密度T值在40岁之后随年龄增加而下降,且出现下降的年龄小于男性;男性血液中铁元素含量在50岁之后随年龄增长而下降;镁元素含量在40岁之后开始呈现下降趋势。结论总矿物质含量在40岁之后随年龄增长而下降,其下降与骨矿物质,全血中铁、镁元素等流失有关。年龄> 40岁人群应动态观察骨矿物质及血中铁、镁等元素浓度变化,如有下降,应及时补充。血钙浓度变化不能及时反映骨矿物质丢失情况。

Objective To investigate the differences of mineral content in adults between different ages and genders in order to provide theoretical basis for individualized mineral supplement and regulation.Methods A retrospective study was performed on 914 cases of patients who took healthy examination from May 2016 to December 2017.According to different ages,patients were divided into the six groups:aged 18-29 group(n=18),aged 30-39 group(n=95),aged 40-49 group(n=295),aged 50-59 group(n=311),aged 60-69 group(n=171)and more than aged 70 group(n=24).The total mineral content in the body,the concentration of copper,iron,magnesium,zinc,calcium,potassium,sodium,chlorine and the t-value and z-value of bone density in the blood were determined respectively,and the differences of mineral content in different ages and genders were analyzed and compared.Results There were statistically significant differences in total mineral content,Z value,iron,magnesium,zinc,potassium,sodium and chlorine between the two genders(P<0.05).The distribution of total mineral content,bone mineral density T value,bone mineral density Z value,magnesium and iron in different age groups of male and female was different(P<0.05).The total mineral content in the body gradually reduced with age after 40;the T value of bone mineral density of female reduced with age after 40,and the decrease occurs earlier than that of male.Iron levels in male′s blood reduced with age after age 50.Magnesium content began to decline after age 40.Conclusion Body mineral contents reduces as age grows after 40,which may be related to the loss of bone mineral,blood Fe and Mg.Adults over 40 should be cared about the earlier changes in bone density and mineral such as Fe and Mg concentrations in blood.Mineral complements may be needed in these individuals.Blood Ca is not an early indicator of osteopenia.