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阻塞性睡眠呼吸暂停综合征患者血浆中ghrelin、炎性因子与心肌早期损伤相关 被引量:2

Correlation between serum ghrelin,inflammatory factors and early cardiac injury in patients with obstructive sleep apnea syndrome
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摘要 阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)现已成为危及公众健康的主要问题,严重影响患者的生存质量。以间歇性低氧为特征OSA常并发心血管疾病,但病理机制尚不明确。胃饥饿素(ghrelin)具有抗感染、抗氧化和抗凋亡保护心血管的功能[1]。然而,有关Ghrelin与不同严重程度的OSA患者心脏早期损伤研究少见报道。鉴于此,本研究通过检测不同程度OSA患者的血浆Ghrelin、炎性因子和心肌早期损伤标志物水平,探讨Ghrelin、炎性因子与心肌早期损伤的关系。
作者 李杰茹 高秀华 韩聚强 康立英 罗文彦 吉恩生 LI Jie-ru;GAO Xiu-hua;HAN Ju-qiang;KANG Li-ying;LUO Wen-yan;JI En-sheng
出处 《基础医学与临床》 CSCD 2019年第2期243-244,共2页 Basic and Clinical Medicine
基金 河北省科技厅计划项目(18277786D)
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