摘要
铁死亡是调节性细胞死亡的一种形式,其特征在于铁依赖性脂质过氧化氢在细胞内积聚过多。铁死亡与哺乳动物多种疾病的发生发展都有关系。突出铁死亡与哺乳动物疾病的联系,可以为临床疾病的诊治提供一个新的方向。
Ferroptosis is a new form of regulatory cell death characterized by the excessive accumulation of iron-dependent lipid hydroperoxide within the cell.It is related to the occurrence and development of many mammalian diseases.Highlighting the relationship between ferroptosis and mammalian diseases can provide a potential strategy for the treatment of clinical diseases.
作者
李博文
王志维
LI Bo-wen;WANG Zhi-wei(Department of Cardiovascular Surgery,Renmin Hospital of Wuhan University,Wuhan 430060,China)
出处
《基础医学与临床》
CSCD
2019年第2期247-251,共5页
Basic and Clinical Medicine
基金
国家自然科学基金(81570428)
关键词
铁死亡
机制
疾病
ferroptosis
mechanisms
diseases
