神经外科住院患者抗菌药物临床用药分析

Analysis of clinical application of antibiotics for inpatients in neurosurgery

目的探讨遂宁市中心医院神经外科住院患者抗菌药物的临床用药特点。方法依据相关指导原则,综合评价分析遂宁市中心医院神经一病区2018年5-7月收治的171例患者住院时抗菌药物的临床应用情况。结果 171例患者使用抗微生物系统药物占比最高达29%,按金额排序前3位分别是注射用美罗培南、注射用丙戊酸钠、注射用乌拉地尔。抗生素使用排前3位的分别是注射用美罗培南、注射用头孢哌酮钠舒巴坦钠、注射用哌拉西林钠舒巴坦钠。用药频度排序前3位的是左氧氟沙星注射液、头孢曲松注射液、注射用哌拉西林钠舒巴坦钠。结论神经一病区院患者以脑出血和神经性疾病为主,用药以抗微生物和神经系统药物为主,药物使用与收治病人类型基本相符,临床用药基本合理。

Objective To explore the clinical characteristics of antimicrobial agents for hospitalized patients in the Neurosurgery Department of Suining Central Hospital.Methods According to relevant guiding principles,clinical application of antibacterial agents in 171 patients admitted to the First Ward of Neurosurgery in the hospital from May 2018 to July 2018 was comprehensively evaluated and analyzed.Results The proportion of 171 patients using anti-microbial drugs was up to 29%,and the top three in order of amount were meropenem,sodium valproate and urapidil for injection.The top three antibiotics are meropenem,cefoperazone sodium-sulbactam sodium for injection and piperacillin sodium-sulbactam sodium for injection.The top three in the frequency order were levofloxacin injection,ceftriaxone injection and piperacillin sodium-sulbactam sodium for injection.Conclusion The inpatients in the Neurosurgery Department are mainly with cerebral hemorrhage and neurological diseases,and the drugs are mainly anti-microbial and nervous system drugs.The use of drugs is basically consistent with the types of patients treated,and the clinical medication is basically reasonable.