摘要
目的通过分析连云港市某医院2016年7—12月住院病人应用降脂药阿托伐他汀的情况,为临床合理用药提供参考。方法从医院信息系统提取阿托伐他汀使用的病人信息,包括年龄、性别、诊断和科室等,以及阿托伐他汀的种类、规格、用法、用量、药品单价和消耗数量等信息。从病人基本情况、药物使用情况和药物利用指标这三方面进行评价。以限定日剂量(DDD)、用药频度(DDDs)和日均费用(DDC)为考查指标进行分析,统计阿托伐他汀的用药需求和用药趋势。结果 2016年7—12月住院病人中阿托伐他汀的使用率为5.9%,年龄为(67.80±12.58)岁,其中男性高于女性。使用人群主要以心脑血管疾病居多,肺部疾病、肾脏疾病也有较多应用。使用最多的科室是心血管内科和神经内科,共占63.6%。合理用药分析中,2 302例使用阿托伐他汀的病例中有7例用法用量不适宜。阿托伐他汀钙片的用药金额和DDDs比阿托伐他汀钙胶囊高,DDC也较高。结论通过对院内阿托伐他汀的临床应用分析,了解阿托伐他汀的使用情况。该院阿托伐他汀使用基本合理,也存在不合理用药的情况。
Objective To analyze clinical application of lipid-lowering drug Atorvastatin in a hospital of Lianyungang from July 2016 to December 2016,and to provide reference for clinical rational drug use.Methods The information of patients using Atorvastatin was obtained from the hospital information system including age,gender,diagnosis,department,etc,and drug information such as the type,specification,usage,dosage,unit price and consumption quantity were collected.The basic information of patients,drug use condition and utilization index were evaluated.Defined daily dose(DDD),drug use frequency(DDDs)and average daily cost(DDC)were used as examining indexes for analysis,and the drug demand and using trend of Atorvastatin were statistically analyzed.Results The ratio of hospitalized patients using Atorvastatin from July to December 2016 was 5.9%,the average age was(67.80±12.58)years old,with men higher than women.The population was mainly patients with cardiovascular and cerebrovascular diseases,and lung diseases and kidney diseases.The departments with high frequency of using were those of cardiovascular medicine and neurology,accounting for 63.6%.Rational drug analysis showed that 7 cases of the 2 302 cases had inappropriate use of Atorvastatin.The drug price and use frequency of Atorvastatin calcium tablet were higher than those of Atorvastatin calcium capsule,and its DDC was also higher.Conclusions Based on the analysis of the clinical application of Atorvastatin,the usage of Atorvastatin was known,the use of Atorvastatin in this hospital of Lianyungang was relatively reasonable,but there were still cases of irrational use of drug.
作者
李智
郭金娟
董洁
孙增先
LI Zhi;GUO Jinjuan;DONG Jie;SUN Zengxian(The First People's Hospital of Lianyungang City Affiliated to Xuzhou Medical University,Lianyungang,Jiangsu 222002,China;Xuzhou Medical University,Xuzhou,Jiangsu 221000,China)
出处
《安徽医药》
CAS
2019年第2期411-414,共4页
Anhui Medical and Pharmaceutical Journal
关键词
降脂药
阿托伐他汀
限定日剂量
用药频度
日均费用
Lipid-lowering drug
Atorvastatin
Defined daily dose
Drug use frequency
Average daily cost