如何看待美国感染病学会对拯救脓毒症运动脓毒症指南的质疑

How to view multiple disagreements of IDSA about the Surviving Sepsis Campaign's recommendations

SSC指南(2016)颁布后不久,美国感染病学会(IDSA)公开发表立场陈述文件表示不予认可。文章就区分脓毒症与非感染性综合征、经验性抗生素治疗的启动时机、血培养与静脉导管处理、联合治疗与多药治疗、降钙素原、药代学/药效学、持续抗生素预防治疗和抗生素疗程等8个方面的分歧阐述了自己的观点。IDSA更强调合理应用抗生素以避免不必要的抗生素过度暴露。相关讨论对于优化抗生素治疗颇有价值。

Infectious Diseases Society of America(IDSA)published a POSITION STATEMENT to declare not endorse the Surviving Sepsis Campaign guidelines(2016)which is issused shortly after.The article summarizes some of IDSA's specific concerns about distinguishing sepsis from non-infectious syndromes,time to initiation of empiric antibiotic therapy,blood cultures and iv access catheters,combination and multidrug therapy,procalcitonin,pharmacokinetics/pharmacodynamics,prolonged prophylaxis,and duration of therapy.IDSA pays more attention to reduce the unnecessary overexposure of antibiotics and its perspectives are valuable to optimize antibiotic therapy.