复发鼻咽癌再程放射治疗的研究进展

Advanced in re-radiotherapy for recurrent nasopharyngeal carcinoma

局部和(或)区域复发是鼻咽癌初次根治性放疗失败的常见原因,也是临床上现存的治疗难题。再程放疗是复发鼻咽癌挽救治疗的主要有效手段之一。本文总结了近年来国内外复发鼻咽癌体外放射治疗(包括常规二维、三维适形、调强放疗)、立体定向放疗、近距离放疗、质子和重离子放疗的相关文献,归纳了不同放疗方法的优缺点及疗效。

Local and/or regional recurrence is a common cause of the failure of primary radical radiotherapy for nasopharyngeal carcinoma,and it is also a clinically existing treatment problem.Re-radiation therapy is one of main effective means of treatment for recurrent nasopharyngeal carcinoma.The article summarizes the recent domestic and abroad literatures on radiotherapy in vitro(including conventional two-dimensional,three-dimensional conformal,intensity-modulated radiotherapy),stereotactic radiotherapy,brachytherapy,proton beam and heavy ion therapy for recurrent nasopharyngeal carcinoma,and summarized the advantages and disadvantages of different radiotherapies as well as their efficacies.